Halaven eribulin mesylate 1mg for sale
Specifications for Halaven eribulin mesylate 1mg
Halaven (eribulin)
Brand name----------------Halaven
Generic name--------------eribulin
Dosage form---------------Injection
Dosage--------------------1mg/2ml
Drug class----------------mitotic inhibitors
Company-------------------Eisai Co
Halaven (eribulin) drug information
NDC code----------------------62856-389-01
LOT NO------------------------117405
Expiry Date-------------------03 / 2020
Halaven (eribulin) Usage
* Interferes with the growth and spread of cancer cells in the body
* Used to treat breast cancer that has spread to other parts of the body
* Used to treat soft tissue sarcoma called liposarcoma that cannot be removed by surgery
Halaven (eribulin) Price
Price-------------------$950 .00 USD (Per unit $950.00 USD)
Quantity----------------1 vials
Dosage------------------1mg/2ml
Breast cancer:
Indications for HALAVEN:
Treatment of metastatic breast cancer in patients who have previously received at least two chemotherapeutic regimens for metastatic disease. Prior therapy should have included an anthracycline and a taxane in either the adjuvant or metastatic setting.
Adult:
Give by IV inj over 2–5mins. 1.4mg/m² on Days 1 and 8 of a 21-day cycle. Mild hepatic impairment (Child-Pugh A) or moderate-to-severe renal impairment (CrCl 15–49mL/min): 1.1mg/m² on Days 1 and 8 of a 21-day cycle. Moderate hepatic impairment (Child-Pugh B): 0.7mg/m² on Days 1 and 8 of a 21-day cycle. Hold dose for ANC <1000 3="" 4="" according="" after="" delay="" do="" dose="" full="" grade="" is="" it="" labeling.="" mm="" non-hematological="" not="" or="" p="" platelets="" re-escalate="" reduce="" reduced.="" see="" to="" toxicities.="" toxicities="">1000>
Children:
<18yrs: established.="" not="" p="">18yrs:>
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Halaven (eribulin mesylate)
HALAVEN® (eribulin mesylate) Injection
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Warnings/Precautions:
Monitor CBCs prior to each dose; increase frequency of monitoring if grade 3 or 4 cytopenias develop, delay and reduce subsequent doses if febrile neutropenia or grade 4 neutropenia lasting >7 days develops. Monitor for peripheral neuropathy; withhold dose if grade 3 or 4 peripheral neuropathy develops until resolution to grade 2 or less. Congenital long QT syndrome: avoid. CHF, bradyarrhythmias, electrolyte abnormalities: monitor ECG for prolonged QT interval. Correct electrolyte abnormalities (K+, Mg+) before treatment; monitor. Severe hepatic impairment (Child-Pugh C): insufficient data. Embryo-fetal toxicity. Pregnancy (avoid). Use effective contraception during treatment and for ≥2 weeks (females) or 3.5 months (male partners) after final dose. Nursing mothers: not recommended (during and for 2 weeks after final dose).
Pharmacologic Class:
Non-taxane microtubule dynamics inhibitor.
Interactions:
Caution with other drugs that prolong QT interval (eg, Class IA and III antiarrhythmics); monitor.
Adverse Reactions:
Neutropenia, anemia, asthenia/fatigue, alopecia, peripheral neuropathy, nausea, constipation, abdominal pain, pyrexia, hypokalemia, hypocalcemia; febrile neutropenia, possible QT prolongation, elevated liver enzymes.
Note:
Do not mix with dextrose-containing solutions. Do not administer in same line as other drugs or fluids.
How Supplied:
Single-use vial (2mL)—1
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Halaven (eribulin mesylate)
HALAVEN® (eribulin mesylate) Injection
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