Halaven eribulin mesylate 1mg for sale


Halaven eribulin mesylate 1mg for sale 





Specifications for Halaven eribulin mesylate 1mg


Halaven (eribulin)
     Brand name----------------Halaven
     Generic name--------------eribulin
     Dosage form---------------Injection
     Dosage--------------------1mg/2ml
     Drug class----------------mitotic inhibitors
     Company-------------------Eisai Co


Halaven (eribulin) drug information
       NDC code----------------------62856-389-01
       LOT NO------------------------117405
       Expiry Date-------------------03 / 2020

Halaven (eribulin) Usage
      * Interferes with the growth and spread of cancer cells in the body           
      * Used to treat breast cancer that has spread to other parts of the body
      * Used to treat soft tissue sarcoma called liposarcoma that cannot be removed by surgery             

       
Halaven (eribulin) Price           
      Price-------------------$950 .00 USD (Per unit $950.00 USD)
      Quantity----------------1 vials
      Dosage------------------1mg/2ml



Breast cancer:
Indications for HALAVEN:
Treatment of metastatic breast cancer in patients who have previously received at least two chemotherapeutic regimens for metastatic disease. Prior therapy should have included an anthracycline and a taxane in either the adjuvant or metastatic setting.

Adult:
Give by IV inj over 2–5mins. 1.4mg/m² on Days 1 and 8 of a 21-day cycle. Mild hepatic impairment (Child-Pugh A) or moderate-to-severe renal impairment (CrCl 15–49mL/min): 1.1mg/m² on Days 1 and 8 of a 21-day cycle. Moderate hepatic impairment (Child-Pugh B): 0.7mg/m² on Days 1 and 8 of a 21-day cycle. Hold dose for ANC <1000 3="" 4="" according="" after="" delay="" do="" dose="" full="" grade="" is="" it="" labeling.="" mm="" non-hematological="" not="" or="" p="" platelets="" re-escalate="" reduce="" reduced.="" see="" to="" toxicities.="" toxicities="">

Children:
<18yrs: established.="" not="" p="">

Warnings/Precautions:
Monitor CBCs prior to each dose; increase frequency of monitoring if grade 3 or 4 cytopenias develop, delay and reduce subsequent doses if febrile neutropenia or grade 4 neutropenia lasting >7 days develops. Monitor for peripheral neuropathy; withhold dose if grade 3 or 4 peripheral neuropathy develops until resolution to grade 2 or less. Congenital long QT syndrome: avoid. CHF, bradyarrhythmias, electrolyte abnormalities: monitor ECG for prolonged QT interval. Correct electrolyte abnormalities (K+, Mg+) before treatment; monitor. Severe hepatic impairment (Child-Pugh C): insufficient data. Embryo-fetal toxicity. Pregnancy (avoid). Use effective contraception during treatment and for ≥2 weeks (females) or 3.5 months (male partners) after final dose. Nursing mothers: not recommended (during and for 2 weeks after final dose).

Pharmacologic Class:
Non-taxane microtubule dynamics inhibitor.

Interactions:
Caution with other drugs that prolong QT interval (eg, Class IA and III antiarrhythmics); monitor.

Adverse Reactions:
Neutropenia, anemia, asthenia/fatigue, alopecia, peripheral neuropathy, nausea, constipation, abdominal pain, pyrexia, hypokalemia, hypocalcemia; febrile neutropenia, possible QT prolongation, elevated liver enzymes.

Note:
Do not mix with dextrose-containing solutions. Do not administer in same line as other drugs or fluids.

How Supplied:
Single-use vial (2mL)—1 


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